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Pulmonary Arterial Hypertension eBook Free Download

Pulmonary Arterial Hypertension eBook PDF Free Download

Edited by Robyn J. Barst

Diagnosis and Evidence-Based Treatment

Published by Wiley

About the Book

This Pulmonary Arterial Hypertension is edited by Robyn J. Barst. This First Edition First book dedicated to this disease, previously thought to be incurable, but with the advent of new drugs, now amenable to management and a much improved prognosis for patients. From the PAH Association, the leading experts in field. Incorporates the latest AACP management guidelines. Includes evidence-based treatment algorithms based on the recently updated ACCP Guidelines for Medical Treatment. Aimed at specialists in pulmonology and cardiovascular disease, this volume provides the clinician with the most up to date information on the effective management of PAH.

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What You will Learn

The Topics Covered in this Textbook are

Introduction
Diagnosis and assessment of pulmonary arterial hypertension
Hemodynamics of pulmonary hypertension
Venice classification
Overview of the diagnostic process (algorithm)
Screening (identifying a pre-existing risk)
Detection (discovering pulmonary hypertension)
Definition (diagnosing the clinical context)
Prediction (estimating prognosis)
Principles of follow-up (evaluating and responding to outcome)
Specific tests in the evaluation of pulmonary hypertension
Conventional therapy in pulmonary arterial hypertension
Calcium channel antagonists
Diuretics
Warfarin
Supplemental oxygen
Inotropic therapy
General measures
Conclusions
Prostanoid treatment for pulmonary arterial hypertension
Epoprostenol
Treprostinil
Iloprost
Beraprost
Treatment selection
Conclusions
Endothelin receptor antagonists in pulmonary arterial hypertension
Bosentan
Sitaxsentan
Ambrisentan
Safety and tolerability with endothelin receptor antagonists
Conclusions
Phosphodiesterase-5 inhibitors in pulmonary arterial hypertension
The origins of phosphodiesterase-5 inhibitor development
Pulmonary hypertension as a new indication for phosphodiesterase-5 inhibitor treatment
Role of phosphodiesterase-5 in the pulmonary vasculature
Clinical experience with sildenafil for the treatment of chronic pulmonary hypertension
Pivotal trial and approval of sildenafil for the treatment of pulmonary arterial hypertension (SUPER-1 study)
Other phosphodiesterase-5 inhibitors
Combination therapy
Potential new indications for phosphodiesterase-5 inhibitors outside pulmonary arterial hypertension
Conclusions
Combination therapy for pulmonary arterial hypertension
Background
Combination therapy to date
Conclusions
Interventional and surgical modalities of treatment for pulmonary arterial hypertension
Introduction
Atrial septostomy
Pulmonary endarterectomy in chronic thromboembolic pulmonary hypertension
Lung transplantation for pulmonary hypertension
Conclusions
End points and clinical trial design in pulmonary arterial hypertension: Clinical and regulatory perspectives
Introduction
Trial design
End points in trials of therapy for pulmonary arterial hypertension
Conclusions
Comparative analysis of clinical trials and evidence-based treatment algorithm for pulmonary arterial hypertension
Introduction
Randomized controlled studies
Long-term continuation studies
Combination studies
Evidence-based treatment algorithm
Conclusions
Diagnosis and assessment of non-pulmonary arterial hypertension masquerading as idiopathic pulmonary arterial hypertension: Diastolic heart failure evaluation and interactions
Definition of heart failure
Epidemiology
Physiology
Evaluation of diastolic heart failure: Invasive and noninvasive techniques
Diagnosis and treatment of diastolic dysfunction
Pulmonary hypertension and diastolic dysfunction
Conclusions
Treatment of pulmonary arterial hypertension: A look to the future
Therapy of pulmonary arterial hypertension
Measuring outcomes and monitoring the course of therapy
Conclusions

For Whom is this Book For

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Details

Format of the eBook: PDF      Size: 12.2 MB

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