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Hepatology A Clinical Textbook

Hepatology A Clinical Textbook pdf

Hepatology A Clinical Textbook pdf

Hepatology A Clinical Textbook pdf

Hepatology A Clinical Textbook pdf free download

Hepatology A Clinical Textbook ebook


Hepatology is a rapidly evolving medical field that will continue to grow

and maintain our excitement over the next few decades. Viral hepatitis is

not unlike HIV was 10 or 15 years ago when the retrovirus began to be

better understood and treatable. Today, hepatitis B viral replication can be

suppressed by potent antiviral drugs, although there are risks regarding the

emergence of resistance. Strategies to enhance the eradication rates of HBV

infection still need to be developed. On the other hand, hepatitis C virus

infection can be eradicated by treatment with pegylated interferon plus

ribavirin. However, particularly in those infected by HCV genotype 1, the

sustained virologic response rates are still suboptimal. Many new antiviral

drugs, especially protease and polymerase inhibitors, are currently in

preclinical and clinical development, and the first data from larger clinical

trials provide some optimism that the cure rates for patients with chronic

hepatitis C will be enhanced with these new agents. In other areas of

hepatology, e.g., hereditary and metabolic liver diseases, our knowledge is

rapidly increasing and new therapeutic options are on the horizon.

Are books in rapidly evolving areas such as hepatology the right medium to

gather and summarise the current knowledge? Are these books not likely to

be outdated the very day they are published? This is indeed a challenge that

can be convincingly overcome only by rapid internet-based publishing with

regular updates. Another unmatched advantage of a web-based book is the

free and unrestricted access everywhere. Viral hepatitis and other liver

diseases are a global burden and timely information is important for

physicians, scientists, patients and health care officials all around the world.

The editors of this web-based book – Thomas Berg, Stefan Mauss, Jürgen

Rockstroh, Christoph Sarrazin and Heiner Wedemeyer – are young, bright,

and internationally renowned hepatologists who have created an excellent

state-of-the-art textbook on clinical hepatology. The book is well structured

and written and provides in-depth information without being lengthy or

redundant. I am convinced that all five will remain very active in the field

and will update this book regularly as the science progresses. This e-book

should rapidly become an international standard.

Stefan Zeuzem

Frankfurt, 24 January 2009

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